{
  "_id": "6a3521cf3efcd9bda43e3fd1",
  "Package": "bossR",
  "Title": "Biomarker Optimal Segmentation System",
  "Version": "1.0.4",
  "Authors@R": "c(person(\"Liuyi\", \"Lan\",,\"lly_wine@126.com\", role = c(\"aut\"),\ncomment = c()),\nperson(\"Xing\", \"Li\",,\"lix491@mail.usask.ca\", role = c(\"aut\" ),\ncomment = c(ORCID = \"0000-0002-4186-7909\")),\nperson(\"Xuanjin\", \"Cheng\",,\"jecheng@bcgsc.ca\", role = c(\"aut\"),\ncomment = c()),\nperson(\"Xuekui\", \"Zhang\",,\"ubcxzhang@gmail.com\", role = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0000-0003-4728-2343\")))",
  "Description": "The Biomarker Optimal Segmentation System R package,\n'bossR', is designed for precision medicine, helping to\nidentify individual traits using biomarkers. It focuses on\ndetermining the most effective cutoff value for a continuous\nbiomarker, which is crucial for categorizing patients into two\ngroups with distinctly different clinical outcomes. The package\nsimultaneously finds the optimal cutoff from given candidate\nvalues and tests its significance. Simulation studies\ndemonstrate that 'bossR' offers statistical power and false\npositive control non-inferior to the permutation approach\n(considered the gold standard in this field), while being\nhundreds of times faster.",
  "License": "GPL-3",
  "Encoding": "UTF-8",
  "RoxygenNote": "7.2.3",
  "LazyData": "true",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-06-19 11:00:00 UTC",
    "User": "root"
  },
  "Author": "Liuyi Lan [aut], Xing Li [aut]\n(<https://orcid.org/0000-0002-4186-7909>), Xuanjin Cheng [aut],\nXuekui Zhang [aut, cre]\n(<https://orcid.org/0000-0003-4728-2343>)",
  "Maintainer": "Xuekui Zhang <ubcxzhang@gmail.com>",
  "Repository": "https://ubcxzhang.r-universe.dev",
  "Date/Publication": "2024-01-16 02:40:52 UTC",
  "RemoteUrl": "https://github.com/cran/bossR",
  "RemoteRef": "HEAD",
  "RemoteSha": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
  "MD5sum": "54fcd937af6b35432f30c110a2d9710a",
  "_user": "ubcxzhang",
  "_type": "src",
  "_file": "bossR_1.0.4.tar.gz",
  "_fileid": "c9801c283c7a5b13921079828fef0aa9e40f6b99df99b7e1a225e97b79221733",
  "_filesize": 99862,
  "_sha256": "c9801c283c7a5b13921079828fef0aa9e40f6b99df99b7e1a225e97b79221733",
  "_created": "2026-06-19T11:00:00.000Z",
  "_published": "2026-06-19T11:02:39.587Z",
  "_distro": "noble",
  "_jobs": [
    {
      "job": 82336312660,
      "time": 121,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "7748112041"
    },
    {
      "job": 82336312614,
      "time": 122,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7748112328"
    },
    {
      "job": 82336312637,
      "time": 97,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "7748104800"
    },
    {
      "job": 82336312655,
      "time": 80,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7748099141"
    },
    {
      "job": 82335936145,
      "time": 152,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7748073377"
    },
    {
      "job": 82336312592,
      "time": 91,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7748103356"
    },
    {
      "job": 82336312645,
      "time": 85,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "7748100835"
    },
    {
      "job": 82336312661,
      "time": 67,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "7748095806"
    },
    {
      "job": 82336312622,
      "time": 76,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7748098199"
    }
  ],
  "_buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/cran/bossR",
  "_commit": {
    "id": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
    "author": "Xuekui Zhang <ubcxzhang@gmail.com>",
    "committer": "cran-robot <csardi.gabor+cran@gmail.com>",
    "message": "version 1.0.4\n",
    "time": 1705372852
  },
  "_maintainer": {
    "name": "Xuekui Zhang",
    "email": "ubcxzhang@gmail.com",
    "login": "ubcxzhang",
    "description": "",
    "uuid": 4983857,
    "orcid": "0000-0003-4728-2343"
  },
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 2.10",
      "role": "Depends"
    },
    {
      "package": "mvtnorm",
      "role": "Imports"
    },
    {
      "package": "survival",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    }
  ],
  "_owner": "cran",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_stars": 0,
  "_contributors": [
    {
      "user": "ubcxzhang",
      "count": 1,
      "uuid": 4983857
    }
  ],
  "_userbio": {
    "uuid": 4983857,
    "type": "user",
    "name": "Xuekui Zhang",
    "followers": 14
  },
  "_downloads": {
    "count": 201,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/bossR"
  },
  "_searchresults": 0,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/bossR.html",
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "manual.pdf"
  ],
  "_realowner": "ubcxzhang",
  "_cranurl": false,
  "_releases": [
    {
      "version": "1.0.4",
      "date": "2024-01-15"
    }
  ],
  "_exports": [
    "getOC"
  ],
  "_datasets": [
    {
      "name": "myGene",
      "title": "clinical dataset",
      "object": "myGene",
      "class": [
        "data.frame"
      ],
      "fields": [
        "time",
        "status",
        "X"
      ],
      "rows": 500,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "getbeta",
      "title": "Get regression coefficient",
      "topics": [
        "getbeta"
      ]
    },
    {
      "page": "getOC",
      "title": "Select Optimal cutoff for a biomarker",
      "topics": [
        "getOC"
      ]
    },
    {
      "page": "getpvalue",
      "title": "Computes the distribution function of the multivariate normal distribution",
      "topics": [
        "getpvalue"
      ]
    },
    {
      "page": "myGene",
      "title": "clinical dataset",
      "topics": [
        "myGene"
      ]
    }
  ],
  "_rundeps": [
    "lattice",
    "Matrix",
    "mvtnorm",
    "survival"
  ],
  "_score": 1,
  "_indexed": true,
  "_nocasepkg": "bossr",
  "_universes": [
    "ubcxzhang"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.0.4",
      "date": "2026-06-19T11:01:59.000Z",
      "distro": "noble",
      "commit": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
      "fileid": "100bfec5c710ed7a6f5680bee4ba18d228a7591f9ee233936931ad276ab7f251",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.0.4",
      "date": "2026-06-19T11:02:01.000Z",
      "distro": "noble",
      "commit": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
      "fileid": "395ab3fd85f0d68a5f40923acae412498b511f94cadda12b33da6c5536334a59",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.0.4",
      "date": "2026-06-19T11:01:42.000Z",
      "commit": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
      "fileid": "36ba9d2a035dfa68e4a1b88b73100a93fe9311ad8346559104668f09b5a2e869",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.0.4",
      "date": "2026-06-19T11:01:26.000Z",
      "commit": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
      "fileid": "db82908d8cc06d17acf86f78ca5cb7f8f85a678adad865ffff71f2770440924f",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.0.4",
      "date": "2026-06-19T11:01:53.000Z",
      "commit": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
      "fileid": "6223d15d119b21d2c1be45cb9ccee7a01f6b978786863f26c8eded43aed5dcef",
      "status": "success",
      "buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.0.4",
      "date": "2026-06-19T11:01:19.000Z",
      "commit": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
      "fileid": "be3e0aeac253db8f0f2c8fb2a921b5ef1fdf5301fcc44dcb271fa4a9cd49f766",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.0.4",
      "date": "2026-06-19T11:01:03.000Z",
      "commit": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
      "fileid": "67ad92efd0941cc74e531a95677252e5833b021adfb574938b4602b556c5c237",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.0.4",
      "date": "2026-06-19T11:01:10.000Z",
      "commit": "5c49c6649a250d728e16e578b3c6d193fdf9a58f",
      "fileid": "afa949cd0dfe84080b172fcc9a8ff786e57e53f80e4416ab1f3aa2f20aa4ac36",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/ubcxzhang/actions/runs/27821626354"
    }
  ]
}